The Long-Term Effect of Maternal Obesity on the Cardiovascular Health of the Offspring-Systematic Review

Curr Probl Cardiol. 2024 Jan;49(1 Pt B):102062. doi: 10.1016/j.cpcardiol.2023.102062. Epub 2023 Aug 29.

Abstract

Maternal obesity may affect offspring's cardiovascular health. Our literature search using PubMed, Web of Sciences included original English research and Google Scholar articles published over the past ten years, culminating in 96 articles in this topic. A mother's obesity during pregnancy has a negative impact on the cardiovascular risk for their offspring. Dependence was observed in relation to hypertension, coronary artery disease, stroke, and heart failure. The adverse impact of an abnormal diet in pregnant mice on heart hypertrophy was observed, and was also confirmed in human research. Pregnant women with obesity were at greater risk of having a child with innate heart disease than pregnant women with normal mass. To conclude: mother's obesity has a negative impact on the long-term cardiovascular consequences for their offspring, increasing their risk of high blood pressure, coronary heart disease, stroke and heart failure. It also increases the probability of heart hypertrophy and innate heart defects.

Publication types

  • Systematic Review

MeSH terms

  • Animals
  • Cardiomegaly
  • Child
  • Female
  • Heart Failure*
  • Humans
  • Mice
  • Obesity / complications
  • Obesity / epidemiology
  • Obesity, Maternal* / complications
  • Obesity, Maternal* / epidemiology
  • Pregnancy
  • Stroke*