Updates in the diagnosis and management of small-bowel tumors

Best Pract Res Clin Gastroenterol. 2023 Jun-Aug:64-65:101860. doi: 10.1016/j.bpg.2023.101860. Epub 2023 Aug 12.


Small-bowel tumors represent a rare entity comprising 0.6% of all new cancer cases in the US, and only 3% of all gastrointestinal neoplasms. They are a heterogenous group of neoplasms comprising of about forty different histological subtypes with the most common being adenocarcinoma, neuroendocrine tumors, stromal tumors and lymphomas. Their incidence has been reportedly increasing over recent years, partly owing to the advances and developments in the diagnostic modalities. Small-bowel capsule endoscopy, device assisted enteroscopy and dedicated small-bowel cross-sectional imaging are complimentary tools, supplementing each other in the diagnostic process. Therapeutic management of small-bowel tumors largely depends on the histological type and staging at diagnosis. The aim of the present review article is to discuss relevant advances in the diagnosis and management of small-bowel tumors.

Keywords: CT enterography; Device assisted enteroscopy; MR enterography; Small-bowel GIST; Small-bowel adenocarcinoma; Small-bowel capsule endoscopy; Small-bowel lymphoma; Small-bowel tumors.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma* / pathology
  • Capsule Endoscopy* / methods
  • Humans
  • Intestinal Neoplasms* / diagnostic imaging
  • Intestinal Neoplasms* / therapy
  • Intestine, Small / diagnostic imaging
  • Intestine, Small / pathology
  • Tomography, X-Ray Computed