Neonatal jaundice: its prevalence in Chinese babies and associating factors

Aust Paediatr J. 1986 Aug;22(3):215-9. doi: 10.1111/j.1440-1754.1986.tb00226.x.

Abstract

A prospective study of 1238 full-term Chinese newborn infants was conducted to determine the incidence of neonatal jaundice and associated factors. A significantly more severe degree of hyperbilirubinaemia was present in infants whose ABO blood group was incompatible with that of their mothers and those who were deficient in the enzyme glucose-6-phosphate dehydrogenase (G6PD). Among the remainder, clinical jaundice was present in 87% and 23.9% had a peak serum bilirubin (SB) concentration greater than 204 mumol/l. Factors that were found to have an association with a higher peak SB concentration included: male infants; elder siblings who had a history of neonatal jaundice; and breast-fed infants with or without supplementation with formula feed. Factors that were found to have no significant association with the peak SB concentration were: gestational age; birthweight; the mode of delivery of the infants; maternal consumption of Chinese herbs and syntocinon induction or augmentation of labour.

MeSH terms

  • ABO Blood-Group System
  • Bilirubin / blood
  • Breast Feeding
  • China
  • Female
  • Glucosephosphate Dehydrogenase Deficiency / blood
  • Humans
  • Infant, Newborn / blood
  • Jaundice, Neonatal / blood
  • Jaundice, Neonatal / epidemiology
  • Jaundice, Neonatal / ethnology*
  • Male
  • Prospective Studies
  • Random Allocation
  • Risk
  • Sex Factors

Substances

  • ABO Blood-Group System
  • Bilirubin