Automatic identification of schizophrenia employing EEG records analyzed with deep learning algorithms

Schizophr Res. 2023 Nov:261:36-46. doi: 10.1016/j.schres.2023.09.010. Epub 2023 Sep 8.

Abstract

Electroencephalography is a method of detecting and analyzing electrical activity in the brain. This electrical activity can be recorded and processed to aid in the clinical diagnosis of mental disorders. In this study, a novel system for classifying schizophrenia patients from EEG recordings is presented. The developed algorithm decomposes the EEG signals into a system of radial basis functions using the method of fuzzy means. This decomposition helps to obtain the information from the various electrodes of the EEG and allows separating between healthy controls and patients with schizophrenia. The proposed method has been compared with classical machine learning algorithms, such as, K-Nearest Neighbor, Adaboost, Support Vector Machine, and Bayesian Linear Discriminant Analysis. The results show that the proposed method obtains the highest values in terms of balanced accuracy, recall, precision and F1 score, close to 93 % in all cases. The model developed in this study can be implemented in brain activity analysis systems that help in the prediction of patients with schizophrenia.

Keywords: Deep learning; Electroencephalogram (EEG); Fuzzy means; Neural network; Radial basis function (RBF); Schizophrenia.

MeSH terms

  • Algorithms
  • Bayes Theorem
  • Deep Learning*
  • Electroencephalography / methods
  • Humans
  • Schizophrenia* / diagnosis
  • Signal Processing, Computer-Assisted
  • Support Vector Machine