Nanobioengineered surface comprising carbon based materials for advanced biosensing and biomedical application

Abstract

Carbon-based nanomaterials (CNMs) are at the cutting edge of materials science. Due to their distinctive architectures, substantial surface area, favourable biocompatibility, and reactivity to internal and/or external chemico-physical stimuli, carbon-based nanomaterials are becoming more and more significant in a wide range of applications. Numerous research has been conducted and still is going on to investigate the potential uses of carbon-based hybrid materials for diverse applications such as biosensing, bioimaging, smart drug delivery with the potential for theranostic or combinatorial therapies etc. This review is mainly focused on the classifications and synthesis of various types of CNMs and their electroanalytical application for development of efficient and ultra-sensitive electrochemical biosensors for the point of care diagnosis of fatal and severe diseases at their very initial stage. This review is mainly focused on the classification, synthesis and application of carbon-based material for biosensing applications. The integration of various types of CNMs with nanomaterials, enzymes, redox mediators and biomarkers have been used discussed in development of smart biosensing platform. We have also made an effort to discuss the future prospects for these CNMs in the biosensing area as well as the most recent advancements and applications which will be quite useful for the researchers working across the globe working specially in biosensors field.

Keywords: Biosensors; Carbon allotropes; Carbon nanomaterials; Nanobiocomposites; Nanobioengineering.