Hepatocellular carcinoma (HCC) invades intrahepatic vessels causing tumor thrombosis. Infrequently, there is involvement of the hepatic vein (HV) and inferior vena cava (IVC). In this review, we summarize the epidemiology, classification, clinical features, and management of HCC with HV and IVC invasion. While the involvement of HV and IVC usually portends an overall poor survival, selected patients may be candidates for aggressive treatment and thus improving outcomes.
Keywords: hepatectomy; hepatic vein; hepatocellular carcinoma; inferior vena cava; transarterial chemoembolisation.
© 2023 Indian National Association for Study of the Liver. Published by Elsevier B.V.