An assessment of the effects of adenoid hypertrophy on mucociliary clearance and nasal cytology in children

Int J Pediatr Otorhinolaryngol. 2023 Nov:174:111718. doi: 10.1016/j.ijporl.2023.111718. Epub 2023 Sep 14.

Abstract

Aim/objective: The aim of this study was to demonstrate the benefits of the systematic use of nasal cytology and mucociliary clearance in the diagnostic workup of nasal disorders in children with adenoid hypertrophy (AH) to reach a well-defined diagnosis, establish a rational therapeutic approach, avert from complications, and develop the patient's life quality.

Materials/methods: In this prospective study, a total of 61 pediatric patients (aged 5-12 years) were evaluated. The case group consisted of 31 children with AH symptoms, while the control group comprised 30 children without AH symptoms.Exclusions included previous adenoidectomy/adenotonsillectomy, cardiovascular/neurological diseases, acute/allergic rhinitis, genetic disorders (e.g., Down syndrome), and immunodeficiency. The control group consisted of children without nasal obstruction symptoms and without AH, who admitted for various reasons. Medical history, examinations, fiberoptic nasopharyngoscopy, cephalometric evaluations, AST, and nasal cytology were conducted.

Results: At the end of the study, a significant increase in the mucociliary clearance time was observed in the group with AH compared to the control group (p < 0.05). Although AH may disrupt MCC, there is no correlation between the size of the hypertrophy and MCC time.When the distribution of cells in the nasal cytology is evaluated, no difference was detected between the AH group and control groups.

Conclusion: Nasal mucociliary clearance has been found to be decreased, particularly in the presence of significant AH.

Keywords: Adenoid hypertrophy; Mucociliary clearance; Nasal cytology; Pediatric snoring.

MeSH terms

  • Adenoids*
  • Child
  • Humans
  • Hypertrophy / complications
  • Mucociliary Clearance
  • Prospective Studies
  • Rhinitis, Allergic* / complications