Mediastinal Presentation of Testicular Embryonal Carcinoma

Sanyogita Chandra; Heidi McKean

Mediastinal Presentation of Testicular Embryonal Carcinoma

S D Med. 2023 Aug;76(8):342-344.

Authors

Sanyogita Chandra¹, Heidi McKean^{2

3

4}

Affiliations

¹ University of South Dakota Sanford School of Medicine, Vermillion, South Dakota.
² Prairie Center, Avera McKennan Hospital and University Health Center, Sioux Falls, South Dakota.
³ Avera Medical Group Oncology and Hematology Sioux Falls, South Dakota.
⁴ University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.

PMID: 37734076

Abstract

Testicular embryonal carcinoma is a type of nonseminomatous germ cell tumor (NSGCT) that commonly presents with scrotal swelling due to testicular mass. About half of patients with NSGCTs will present with metastases at initial diagnosis. Rarely, testicular embryonal carcinoma can present primarily in the mediastinum. Treatment is well-studied and effective: chemotherapy with bleomycin, etoposide, and cisplatin. Post-chemotherapy retroperitoneal lymph node dissection (RPLND) is common adjuvant therapy. In this report we present a case of testicular embryonal carcinoma in a 32-year-old Caucasian man. The rarity of the case resides in its presentation: supraclavicular lymphadenopathy and no testicular mass on palpation or scrotal ultrasound.

Publication types

Case Reports

MeSH terms

Adult
Carcinoma, Embryonal* / diagnosis
Etoposide
Humans
Male
Mediastinum
Neoplasms, Germ Cell and Embryonal* / diagnosis
Neoplasms, Germ Cell and Embryonal* / therapy
Testicular Neoplasms* / diagnosis
Testicular Neoplasms* / therapy

Substances

Etoposide