Recent Progress in the Synthesis of Silaspiranes

Abstract

Silaspiranes bearing a spiro-silicon center are promising ring frameworks for the synthesis of novel spirocyclic molecules possessing unique properties. Development of efficient methods towards these ring structures has therefore attracted considerable attentions of synthetic chemists. This minireview highlights the representative advances in the field, and is categorized into four parts according to the ring formation strategies: cyclization, annulation, ring expansion and cycloaddition.

Keywords: C−H silylation; Si−C bond activation; chiral silanes; hydrosilylation; silaspiranes.