Autoimmune encephalitis: A diagnostic enigma

Indian J Med Microbiol. 2023 Nov-Dec:46:100477. doi: 10.1016/j.ijmmb.2023.100477. Epub 2023 Sep 25.

Abstract

Autoimmune encephalitis with anti-NMDA (N-methyl-D-aspartate) receptor encephalitis is the most common type. This condition can be associated with underlying malignancy, making appropriate screening essential. Prompt identification and intervention of autoimmune encephalitis is essential for a successful outcome and full recovery from this serious and potentially fatal condition. Immunotherapy is typically used to suppress the immune response and reduce brain inflammation. The choice of therapy depends on the type and severity of autoimmune encephalitis, as well as the presence of an underlying tumour.

Keywords: Autoimmune encephalitis; Japanese virus encephalitis; NMDAR antibodies.

MeSH terms

  • Autoantibodies
  • Autoimmune Diseases of the Nervous System*
  • Encephalitis* / diagnosis
  • Hashimoto Disease* / diagnosis
  • Hashimoto Disease* / therapy
  • Humans
  • Immunotherapy

Substances

  • Autoantibodies

Supplementary concepts

  • Hashimoto's encephalitis