Esophageal Function and Reflux Evaluations in Lung Transplantation: A Nationwide Survey of UNOS-Accredited Transplant Centers in the United States

Clin Transl Gastroenterol. 2023 Dec 1;14(12):e00641. doi: 10.14309/ctg.0000000000000641.

Abstract

Introduction: Gastroesophageal reflux disease has been associated with worse lung transplant outcomes. We aimed to assess local practices for esophageal function testing (EFT) across transplant centers.

Methods: This was a survey study of all United Network for Organ Sharing-accredited adult lung transplant centers regarding local EFT practice.

Results: Among 39/63 (60%) responded centers, 38.5% required any EFT (35.9% esophageal manometry, 15.4% pH monitoring, and 28.2% pH impedance), while another 28.2% may consider EFT based on symptoms. Five-year transplant volume was higher among centers requiring EFT (253 vs 159, P = 0.04).

Discussion: Only a minority of lung transplant centers routinely obtained EFT, supporting the need for guidelines for standardized reflux/esophageal assessment.

MeSH terms

  • Adult
  • Esophageal pH Monitoring
  • Gastroesophageal Reflux* / complications
  • Gastroesophageal Reflux* / diagnosis
  • Gastroesophageal Reflux* / surgery
  • Humans
  • Lung Transplantation* / adverse effects
  • Retrospective Studies
  • United States / epidemiology