The Current Trend of Radiation Therapy for Patients with Localized Prostate Cancer

Curr Oncol. 2023 Sep 1;30(9):8092-8110. doi: 10.3390/curroncol30090587.


A recent approach to radiotherapy for prostate cancer is the administration of high doses of radiation to the prostate while minimizing the risk of side effects. Thus, image-guided radiotherapy utilizes advanced imaging techniques and is a feasible strategy for increasing the radiation dose. New radioactive particles are another approach to achieving high doses and safe procedures. Prostate brachytherapy is currently considered as a combination therapy. Spacers are useful to protect adjacent organs, specifically the rectum, from excessive radiation exposure.

Keywords: brachytherapy; hydrogel spacer; image-guided radiation therapy; intensity-modulated radiation therapy; metastasis direct therapy; prostate cancer; radiation therapy; stereotactic body radiation therapy; volumetric modulated arc therapy.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Male
  • Prostate / radiation effects
  • Prostatic Neoplasms* / etiology
  • Prostatic Neoplasms* / radiotherapy
  • Radiotherapy Dosage
  • Radiotherapy, Intensity-Modulated* / methods
  • Rectum / radiation effects

Grants and funding

This research was funded by Grants-in-Aid for Scientific Research, Japan (grant number: 20K09553).