Study on anxiety, depression, and subjective wellbeing of patients with bladder cancer in their different chemotherapy stages

Abstract

Aims and objectives: This study aims to explore the changes in anxiety, depression, and subjective wellbeing in patients with bladder perfusion during different stages of their chemotherapy, and analyze the correlation among their anxiety, depression, and subjective wellbeing.

Methods: A total of 174 patients with bladder cancer who received bladder perfusion chemotherapy were selected. The questionnaire survey was conducted with SAS, SDS, and GWB. The patients were surveyed and the data were analyzed.

Results: The results of patients' anxiety, depression, and subjective wellbeing show a dynamic change trend. The change is most obvious after 1 month of chemotherapy and tends to be flat after 3 months of chemotherapy. The scores of anxiety, depression, and subjective wellbeing in patients with bladder perfusion at different stages are statistically significant (P < 0.05). There is a negative correlation among anxiety, depression, and subjective wellbeing in patients (r = -0.605, 0.601).

Conclusion: Patients' emotions change obviously in the first 3 months of their chemotherapy. Clinical workers can take active intervention measures in this period, guide patients to relieve their anxiety and depression, increase their subjective wellbeing level, and improve their quality of life, which is helpful to ensure the successful completion of chemotherapy.

Keywords: anxiety; bladder cancer; depression; perfusion chemotherapy; subjective wellbeing.