A case of pulmonary nocardiosis with Nocardia brasiliensis spread from a post-traumatic cutaneous infection in an immunocompetent patient

Respirol Case Rep. 2023 Sep 26;11(10):e01227. doi: 10.1002/rcr2.1227. eCollection 2023 Oct.

Abstract

Nocardia is an aerobic Gram-positive bacterium found in the environment, including soil and water. Nocardia brasiliensis is reportedly associated with cutaneous infections, and disseminated disease is typically detected in immunocompromised individuals. We present a rare case of disseminated nocardiosis with N. brasiliensis in an immunocompetent patient. An 82-year-old male, who had a left elbow injury 2 months prior to the first visit, presented with bilateral multiple lung nodules. N. brasiliensis was identified in both sputum and pus specimens, we concluded that the N. brasiliensis had spread from the primary cutaneous lesion. The patient was treated with antibiotics and had a favourable clinical course. As the present case report demonstrates, disseminated nocardiosis caused by this species can progress from a primary cutaneous lesion even in immunocompetent individuals, if the initiation of appropriate treatment is delayed. Therefore, careful evaluation is warranted when Nocardia species are detected.

Keywords: Nocardia brasiliensis; cutaneous infection; disseminated nocardiosis.

Publication types

  • Case Reports