Developments in Dedicated Prostate PET Instrumentation

Abstract

This article summarizes the evolution of dedicated prostate PET instrumentation. It starts by introducing prostate cancer, as well as the most common diagnostic and staging methods that are used in the clinics. Then, it describes the key aspects of PET detectors and their assembly in full PET scanners highlighting the most suitable geometries for prostate examination, and a review on the existing prostate dedicated PET. Finally, the next steps for extending the use of PET in the daily diagnose, staging, and image-guided biopsy of patients with prostate cancer are discussed.

Keywords: Organ-dedicated PET; Positron emission tomography (PET); Prostate cancer (PCa); Prostate-specific membrane antigen (PSMA); Transrectal PET probe.