In minor, nondisabling, acute ischemic stroke, DAPT was noninferior to IV alteplase for excellent functional outcome at 90 d

Ann Intern Med. 2023 Oct;176(10):JC110. doi: 10.7326/J23-0072. Epub 2023 Oct 3.

Abstract

Chen HS, Cui Y, Zhou ZH, et al; ARAMIS Investigators. Dual antiplatelet therapy vs alteplase for patients with minor nondisabling acute ischemic stroke: the ARAMIS randomized clinical trial. JAMA. 2023;329:2135-2144. 37367978.

Publication types

  • Randomized Controlled Trial
  • Comment

MeSH terms

  • Humans
  • Ischemic Stroke* / drug therapy
  • Platelet Aggregation Inhibitors / therapeutic use
  • Tissue Plasminogen Activator / therapeutic use
  • Treatment Outcome

Substances

  • Platelet Aggregation Inhibitors
  • Tissue Plasminogen Activator