Psycho-social predictors of chronicity in depressed patients

Br J Psychiatry. 1986 Jun;148:648-54. doi: 10.1192/bjp.148.6.648.


Nineteen patients with an episode of major depressive disorder who did not recover within two years of prospective follow-up were compared with an equal number who recovered within a year of the initial evaluation and remained well through the two-year follow-up date. The groups were individually matched for age, sex, primary/secondary status, and prior duration of episode. The only psycho-social variable that predicted chronicity was increased neuroticism on self-report personality inventories administered during the index evaluation. Early loss, recent life events, and recent social supports were not predictive of outcome.

MeSH terms

  • Adult
  • Affective Symptoms / complications
  • Chronic Disease
  • Depressive Disorder / psychology*
  • Depressive Disorder / therapy
  • Female
  • Humans
  • Interpersonal Relations
  • Life Change Events
  • Male
  • Personality Disorders / complications
  • Prognosis
  • Psychiatric Status Rating Scales
  • Self Concept
  • Social Support