Increased 68 Ga-FAPI Activity in Primary Small Cell Neuroendocrine Carcinoma of the Gallbladder

Longlan Chen; Rui Sun; Lisheng Liu; Jun Hua; Xiaoliang Chen

doi:10.1097/RLU.0000000000004855

Increased 68 Ga-FAPI Activity in Primary Small Cell Neuroendocrine Carcinoma of the Gallbladder

Clin Nucl Med. 2023 Nov 1;48(11):1003-1005. doi: 10.1097/RLU.0000000000004855. Epub 2023 Sep 18.

Authors

Longlan Chen¹, Rui Sun, Lisheng Liu¹, Jun Hua¹, Xiaoliang Chen¹

Affiliation

¹ From the Department of Nuclear Medicine, Chongqing University Cancer Hospital, Chongqing.

PMID: 37796160
DOI: 10.1097/RLU.0000000000004855

Abstract

Primary small cell neuroendocrine carcinomas are extremely rare heterogeneous neoplasms. We present 68 Ga-FAPI (fibroblast activation protein inhibitor) PET/CT findings of small cell neuroendocrine carcinoma of the gallbladder in a 57-year-old woman. This rare gallbladder small cell neuroendocrine carcinoma demonstrated intense tracer uptake on 68 Ga-FAPI PET/CT. This demonstrates the potential value of 68 Ga-FAPI PET/CT for evaluation of gallbladder small cell neuroendocrine carcinoma.

Publication types

Case Reports

MeSH terms

Carcinoma, Neuroendocrine* / diagnostic imaging
Carcinoma, Small Cell* / diagnostic imaging
Female
Fluorodeoxyglucose F18
Gallbladder Neoplasms* / diagnostic imaging
Gallium Radioisotopes
Humans
Middle Aged
Positron Emission Tomography Computed Tomography

Substances

Fluorodeoxyglucose F18
Gallium-68
Gallium Radioisotopes