Absorption of an oral glucose load in the dog

Horm Metab Res. 1986 Sep;18(9):587-9. doi: 10.1055/s-2007-1012381.

Abstract

Absorption of glucose from the gut was estimated in trained unanesthetized dogs given a glucose load of 1-25 g (14C)glucose by stomach tube. The rate of absorption of glucose was calculated from the concentration and specific activity of glucose in the portal vein and in an "arterialized" peripheral vein. When the rate was integrated over time it was found that 94 +/- 4% of the administered glucose was recovered from the portal vein as glucose; this was unrelated to the size of the glucose load. It is concluded that absorption does not entail a significant loss or conversion to glucose metabolites.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Glucose
  • Carbon Radioisotopes
  • Dogs
  • Glucose / metabolism*
  • Intestinal Absorption*
  • Kinetics
  • Portal Vein

Substances

  • Blood Glucose
  • Carbon Radioisotopes
  • Glucose