Using Human iPSC-Derived Peripheral Nervous System Disease Models for Drug Discovery

Abstract

Induced pluripotent stem cells (IPSCs), with their remarkable ability to differentiate into various cell types, including peripheral nervous system cells such as neurons and glial cells, offer an excellent platform for in vitro disease modeling. These iPSC-derived disease models have proven valuable in drug discovery, as they provide more precise simulations of a patient's disease state and allow for the assessment of potential therapeutic effectiveness and safety.

Keywords: Drug discovery, Induced pluripotent stem cell, Peripheral nervous system.