Novel regulators of mitochondrial genome integrity

J Biosci. 2023:48:39.

Abstract

Mitochondrial genomes are unusual in that they have very low mutation rates in coding sequences when compared with animals, yeast, and bacteria. It has been proposed that the mitochondrial (mt) DNA damage is preferentially repaired by homologous recombination (HR). In this short review, we summarize and discuss the well-established and recently identified pathways that help in maintaining the integrity of plant mitochondrial genomes.

MeSH terms

  • Animals
  • DNA, Mitochondrial / genetics
  • DNA, Mitochondrial / metabolism
  • Genome, Mitochondrial* / genetics
  • Genome, Plant
  • Homologous Recombination
  • Mitochondria / genetics
  • Mitochondria / metabolism
  • Plants / genetics
  • Saccharomyces cerevisiae / genetics

Substances

  • DNA, Mitochondrial