Towards more accurate pharmacogenomic variant effect predictions

Pharmacogenomics. 2023 Nov;24(16):841-844. doi: 10.2217/pgs-2023-0187. Epub 2023 Oct 17.


Tweetable abstract Accurate variant interpretation has become a key bottleneck for the translation of an individual's pharmacogenome into actionable recommendations. We recommend an integrated use of multiplexed assays, structure-based predictions and biobank data to develop more accurate effect predictors.

Keywords: genomic medicine; personalized drug response; precision medicine; variant of unknown significance.

Publication types

  • Editorial

MeSH terms

  • Humans
  • Pharmacogenomic Variants* / genetics
  • Precision Medicine*