A novel method of prosthetic leaflet modification to enable transcatheter mitral valve-in-valve replacement

Catheter Cardiovasc Interv. 2023 Nov;102(6):1149-1153. doi: 10.1002/ccd.30872. Epub 2023 Oct 19.


Left ventricular outflow tract (LVOT) obstruction from the displaced prosthetic anterior mitral leaflet is a life-threatening complication that can occur during valve-in-valve (ViV) transcatheter mitral valve replacement (TMVR). Laceration of the anterior mitral leaflet to prevent outflow obstruction is a well-established transcatheter technique to mitigate the risk of LVOT obstruction in high-risk anatomies. In this report, we present a novel transseptal technique of prosthetic leaflet modification to prevent LVOT obstruction during ViV TMVR.

Keywords: LVOT; TMVR; leaflet modification; valve-in-valve.

Publication types

  • Case Reports

MeSH terms

  • Cardiac Catheterization / adverse effects
  • Cardiac Catheterization / methods
  • Heart Valve Prosthesis Implantation* / adverse effects
  • Heart Valve Prosthesis Implantation* / methods
  • Heart Valve Prosthesis* / adverse effects
  • Humans
  • Mitral Valve / diagnostic imaging
  • Mitral Valve / surgery
  • Risk Factors
  • Treatment Outcome
  • Ventricular Outflow Obstruction* / diagnostic imaging
  • Ventricular Outflow Obstruction* / etiology
  • Ventricular Outflow Obstruction* / prevention & control
  • Ventricular Outflow Obstruction, Left*