STAT5-mediated transcription of miR-33-5p in Mycoplasma gallisepticum-infected DF-1 cells

Avian Pathol. 2024 Feb;53(1):68-79. doi: 10.1080/03079457.2023.2272617. Epub 2023 Dec 19.

Abstract

MG-HS regulates the expression of transcription factor STAT5.Transcription factor STAT5 can target miR-33-5p promoter element.MG-influenced STAT5 regulates miR-33-5p and its target gene expression.

Keywords: JNK1; Mir-33-5p; Mycoplasma gallisepticum HS strain; STAT5; chicken; inflammation.

MeSH terms

  • Animals
  • Cell Line
  • Chickens / genetics
  • Fibroblasts
  • MicroRNAs* / genetics
  • MicroRNAs* / metabolism
  • Mycoplasma Infections* / veterinary
  • Mycoplasma gallisepticum* / genetics
  • STAT5 Transcription Factor / genetics
  • STAT5 Transcription Factor / metabolism

Substances

  • MicroRNAs
  • STAT5 Transcription Factor