Bioactive compound, polyphenol content, and antioxidant activity of Asparagus racemosus Linn. root extract

Nat Prod Res. 2024 Nov;38(22):4065-4070. doi: 10.1080/14786419.2023.2272029. Epub 2023 Oct 24.

Abstract

Asparagus racemosus Linn. is an ethnopharmacologically important plant having extensive uses in Ayurveda, Unani, and Siddha. This study was carried out to evaluate the chemical profile of A. racemosus Linn. using GC-MS and FT-IR analysis, and its polyphenol content and antioxidant effects. Plants were collected from Bhujiyaghat, Nainital (29.3159° N, 79.5245° E) in Kumaun Himalayas. GC-MS with FT-IR analysis identified multiple functional groups, including carboxylic acid derivatives. Methyl 11, 12-octadecadienoate, was screened as the major compounds by GC-MS. A. racemosus contains a high concentration of phenols (80.92 ± 0.57 mg of GAE/g of DW), flavonoids (58.22 ± 1.62 mg of QE/g of DW), and tannins (86.77 ± 0.81 mg of TAE/g of DW). DPPH (24.63 ± 0.21 g/ml) and FRAP (72.49483 ± 0.130549 mg of AAE/g of DW) assays revealed the presence of significant antioxidant activity in A. racemosus.

Keywords: Antioxidants; Asparagus; bioactive compounds; phytochemicals; polyphenols.

MeSH terms

  • Antioxidants* / chemistry
  • Antioxidants* / pharmacology
  • Asparagus Plant* / chemistry
  • Flavonoids* / analysis
  • Flavonoids* / chemistry
  • Flavonoids* / pharmacology
  • Gas Chromatography-Mass Spectrometry
  • Phenols / analysis
  • Phenols / chemistry
  • Phenols / pharmacology
  • Plant Extracts* / chemistry
  • Plant Extracts* / pharmacology
  • Plant Roots* / chemistry
  • Polyphenols* / analysis
  • Polyphenols* / chemistry
  • Polyphenols* / pharmacology
  • Spectroscopy, Fourier Transform Infrared
  • Tannins / analysis
  • Tannins / chemistry

Substances

  • Antioxidants
  • Polyphenols
  • Plant Extracts
  • Flavonoids
  • Phenols
  • Tannins