Efficacy evaluation of endolift laser for treatment of nasolabial folds and marionette lines

Skin Res Technol. 2023 Oct;29(10):e13480. doi: 10.1111/srt.13480.


Background: The nasolabial folds are the most marked sign of aging. Endolift laser was used for the treatment of nasolabial folds and marionette lines (one of the facial danger zones).

Methods: Ten female subjects were engaged in this study. Patients underwent Endolift laser for nasolabial folds and marionette lines treatment. The efficacy of the Endolift technique on the nasolabial folds and marionette lines was evaluated by biometric assessment with Cutometer, Visioface, and the Skin Ultrasound Imaging system. Also, patient's satisfaction and blinded dermatologists' assessment were assessed.

Results: The Visoface results displayed that the Endolift laser treatment significantly declined the depth and area of the nasolabial wrinkles. The skin ultrasonography results reported that the epidermis and dermis density and thickness were significantly increased. Also, the cutometer outcomes showed that the Endolift laser treatment can increase skin elasticity. The results showed that a large number of patients were very satisfied with the technique.

Conclusion: In conclusion, Endolift laser has an effective technique for decreasing the nasolabial folds, marionette lines, and improve the appearance of the face without any sever side effect. This technique does not need general anesthesia and recovery time.

Keywords: endolift laser; laser treatment; marionette lines; nasolabial folds; treatment.

MeSH terms

  • Cosmetic Techniques* / adverse effects
  • Female
  • Humans
  • Lasers
  • Nasolabial Fold / surgery
  • Rejuvenation
  • Skin
  • Skin Aging*
  • Treatment Outcome