Ischemic Stroke in a Seven-Year-Old Female With Down Syndrome and Newly Discovered Moyamoya Syndrome

Daniel A Brenner; Elizabeth Flatley; Sushmitha Medappa Maruvanda; Nicholas B Dadario; Daniel J Valdivia; Meenakshi Khosla

doi:10.7759/cureus.45893

Ischemic Stroke in a Seven-Year-Old Female With Down Syndrome and Newly Discovered Moyamoya Syndrome

Cureus. 2023 Sep 25;15(9):e45893. doi: 10.7759/cureus.45893. eCollection 2023 Sep.

Authors

Daniel A Brenner¹, Elizabeth Flatley², Sushmitha Medappa Maruvanda³, Nicholas B Dadario¹, Daniel J Valdivia¹, Meenakshi Khosla³

Affiliations

¹ Neurosurgery, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, USA.
² Pediatrics, Robert Wood Johnson Medical School, Rutgers University, New Brunswick, USA.
³ Pediatrics, Saint Peter's University Hospital, New Brunswick, USA.

Abstract

Moyamoya represents a rare, progressive cerebrovascular disease, characterized by a gradual stenosis of the intracranial internal carotid arteries, thereby increasing the risk of stroke. Down syndrome is known to be a predisposing factor for Moyamoya syndrome. This review discusses a distinctive case of a seven-year-old female with Down syndrome who manifested with Moyamoya syndrome, evident from acute stroke-like symptoms.

Keywords: cerebrovascular; down syndrome (ds); moyamoya; moyamoya disease; moyamoya syndrome; pediatric moyamoya syndrome; pediatrics; stroke.

Publication types

Case Reports