Experimental transvitreal cyanoacrylate retinopexy through silicone oil

Am J Ophthalmol. 1986 Dec 15;102(6):717-22. doi: 10.1016/0002-9394(86)90398-3.


We evaluated the use of transvitreal cyanoacrylate retinopexy in the treatment of experimental rhegmatogenous retinal detachment during vitreous surgery in rabbit eyes filled with silicone oil. The view to the fundus was superior to that obtained in our previous model of cyanoacrylate retinopexy in the air-filled eye. Glue delivery was consequently both easier and more precise through silicone oil relative to air. The chorioretinal adhesions produced with cyanoacrylate tissue adhesive were compared with those produced by transscleral retinal cryopexy and were found to be more rapid in onset as well as stronger. An exaggerated tissue response adjacent to the cyanoacrylate site suggested a potential toxic chemical or thermal reaction, or both, to the tissue adhesive, but there was no evidence of any distant ocular effects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Enbucrilate / therapeutic use*
  • Fundus Oculi
  • Postoperative Period
  • Rabbits
  • Retina / pathology
  • Retinal Detachment / pathology
  • Retinal Detachment / surgery*
  • Silicone Oils*
  • Tissue Adhesives / therapeutic use*
  • Vitreous Body / surgery*


  • Silicone Oils
  • Tissue Adhesives
  • Enbucrilate