Can prophylactic HPV vaccination reduce the recurrence of cervical lesions after surgery? Review and prospect

Ling Han; Bingyi Zhang

doi:10.1186/s13027-023-00547-2

Can prophylactic HPV vaccination reduce the recurrence of cervical lesions after surgery? Review and prospect

Infect Agent Cancer. 2023 Oct 29;18(1):66. doi: 10.1186/s13027-023-00547-2.

Authors

Ling Han^{1

2}, Bingyi Zhang^{3

4}

Affiliations

¹ Department of Obstetrics and Gynecology, The First College of Clinical Medical Science, China Three Gorges University, Yichang City, Hubei Province, People's Republic of China.
² Department of Obstetrics and Gynecology, Yichang Central People's Hospital, Yichang City, Hubei Province, People's Republic of China.
³ Department of Ultrasound Imaging, The First College of Clinical Medical Science,, China Three Gorges University, Jiefang Road 2, Yichang City, 443003, Hubei Province, People's Republic of China. 10978649@qq.com.
⁴ Department of Ultrasound Imaging, Yichang Central People's Hospital, Jiefang Road 2, Yichang City, 443003, Hubei Province, People's Republic of China. 10978649@qq.com.

Abstract

Women with HSIL typically undergo conization/LEEP to remove cervical lesions, but the risk of HSIL lesions returning after surgical treatment remains higher than in the general population. HPV vaccination is essential to prevent cervical cancer. However, the effect of prophylactic HPV vaccination on reducing the risk of recurrent cervical lesions after surgical treatment remains unclear. This review aims to analyze and summarize the latest literature on the role of prophylactic HPV vaccine in reducing the recurrence of cervical lesions after surgery in patients with HSIL, and to review and update the history, efficacy, effectiveness and safety of HPV vaccine, focusing on the current status of global HPV vaccine implementation and obstacles.

Keywords: CIN; Cervical lesions; HPV; HSIL; Vaccination.

Publication types

Review