Primary Cutaneous Marginal Zone Lymphoma following Repeated Inflammation Caused by Hair Dyeing

Jun Hyo Lee; Ui Hyeon Jo; Tae Min Kim; Dae Hun Suh

doi:10.1159/000533516

Primary Cutaneous Marginal Zone Lymphoma following Repeated Inflammation Caused by Hair Dyeing

Case Rep Dermatol. 2023 Sep 6;15(1):152-155. doi: 10.1159/000533516. eCollection 2023 Jan-Dec.

Authors

Jun Hyo Lee^{1

2}, Ui Hyeon Jo¹, Tae Min Kim³, Dae Hun Suh^{1

2}

Affiliations

¹ Department of Dermatology, Seoul National University College of Medicine, Seoul, South Korea.
² Acne, Rosacea, Seborrheic Dermatitis and Hidradenitis Suppurativa Research Laboratory, Seoul National University Hospital, Seoul, South Korea.
³ Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.

Abstract

Primary cutaneous marginal zone lymphoma (PCMZL) is a rare form of B-cell lymphoma that primarily affects the skin. Chronic antigen stimulation has been implicated in its development, with cases associated with various triggers. We present a case of PCMZL following chronic inflammation caused by long-term hair dyeing. A 75-year-old woman with a history of repeated inflammation and itching after hair dyeing for 30 years presented with persistent red-to-violaceous patches and plaques on her scalp. Despite receiving topical corticosteroid treatment for 10 years, the lesions remained. Pathological examinations confirmed the diagnosis of PCMZL. The patient achieved complete remission after radiotherapy. This case underscores the potential link between chronic inflammation and the development of PCMZL.

Keywords: B-cells; Case report; Hair dyes; Inflammation; Marginal zone B-cell lymphoma; Physiopathology.

Publication types

Case Reports

Grants and funding

No financial support was provided for this research.