Modulation of Trust in Borderline Personality Disorder by Script-Based Imaginal Exposure to Betrayal

J Pers Disord. 2023 Oct;37(5):508-524. doi: 10.1521/pedi.2023.37.5.508.

Abstract

Interpersonal and trust-related difficulties are central features of borderline personality disorder (BPD). In this study, we applied script-driven betrayal imagery to evoke mistrustful behavior in a social reinforcement learning task. In 21 BPD and 20 healthy control (HC) participants, we compared this approach to the standard confederate paradigm used in research studies. The script-driven imagery evoked a transient increase in negative affect and also decreased trusting behavior to a similar degree in both groups. Across conditions, we also replicated previously reported between-group differences in negative affect (increased in BPD) and task behavior (more sensitive to social cues in BPD). These results support the validity of script-driven imagery as an alternative social task stimulus. This script-driven imagery approach is appealing for clinical research studies on reinforcement learning because it eliminates deception, scales easily, and evokes disorder-specific states of social difficulty.

Keywords: borderline personality disorder; confederate; reinforcement learning; script-driven imagery; social learning; trust.

MeSH terms

  • Betrayal
  • Borderline Personality Disorder*
  • Humans
  • Trust*