Hydrogels in endovascular embolization. II. Clinical use of spherical particles

Biomaterials. 1986 Nov;7(6):467-70. doi: 10.1016/0142-9612(86)90037-2.


In this study we report the results of clinical experiments, obtained with spherical particles made from poly(2-hydroxyethyl methacrylate) used in the embolization of arteriovenous anastomoses, in the suppression of pulmonary haemorrhage and haemoptysis and in the occlusion of some other arteries. So far we have used these particles in the treatment of 187 patients. It must be stressed that the advantage of spherical particles consists in the simplicity of their introduction into the blood vessel through a catheter, while in the blood vessel itself the particle swells in blood still more, when compared with the particle size in saline. This results in an immediate and permanent haemostatic effect. No revascularization occurs.

MeSH terms

  • Embolization, Therapeutic / instrumentation*
  • Gels
  • Hemorrhage / therapy*
  • Humans
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / therapy*
  • Polyhydroxyethyl Methacrylate / therapeutic use*
  • Polymethacrylic Acids / therapeutic use*
  • Radiography
  • Time Factors


  • Gels
  • Polymethacrylic Acids
  • Polyhydroxyethyl Methacrylate