Predictors of multiple dilations and functional outcomes after total laryngectomy and laryngopharyngectomy

Head Neck. 2024 Jan;46(1):138-144. doi: 10.1002/hed.27545. Epub 2023 Oct 31.

Abstract

Background: Following total laryngectomy (TL) or laryngopharyngectomy (TLP), patients may develop strictures that require multiple dilations to treat. However, the risk factors associated with dysphagia refractory to a single dilation are unknown.

Methods: Single-institution retrospective review of patients who underwent at least one stricture dilation after TL/TLP between March 2013 and March 2022.

Results: A total of 49 patients underwent stricture dilation after TL/TLP. Thirty-five (71%) underwent multiple dilations. Pharyngocutaneous fistula, primary chemoradiation therapy, and a shorter time interval from TL/TLP to first dilation were independently associated with dysphagia requiring multiple dilations. Patients in the multiple dilations group had a higher rate of limited diet and G-tube dependence compared to patients in the single dilation group.

Conclusions: Shorter time interval to stricture formation is a prognostic indicator of the need for multiple dilations following TL/TLP. Patients requiring multiple dilations are at increased risk of persistent dysphagia long-term.

Keywords: functional outcomes; larynx cancer; stricture; total laryngectomy; total laryngopharyngectomy.

MeSH terms

  • Constriction, Pathologic / complications
  • Deglutition Disorders* / etiology
  • Dilatation / adverse effects
  • Esophageal Stenosis* / complications
  • Esophageal Stenosis* / therapy
  • Humans
  • Laryngectomy / adverse effects
  • Retrospective Studies
  • Treatment Outcome