Implementation of IT supported standardization of individualized hydrocortisone management for treatment of patients with adrenal insufficiency

J Pediatr Endocrinol Metab. 2023 Nov 3;36(12):1175-1180. doi: 10.1515/jpem-2023-0313. Print 2023 Dec 15.

Abstract

Objectives: Hydrocortisone stress dosing guidelines for children with adrenal insufficiency (AI) recommend a wide range of acceptable stress doses. This has led to variability in dosing recommendations resulting in confusion among endocrine, non-endocrine providers and patient families. This quality improvement project sought to standardize documentation and hydrocortisone stress dosing within our pediatric endocrine division to optimize communication regarding AI management.

Methods: Plan-Do-Study-Act (PDSA) cycle one aimed to address documentation of components important in AI management including body surface area (BSA), home daily dose, home stress dose, in-patient stress dose, procedure dose and crisis dose using a smart phrase within the electronic health record (EHR). To automate the process, PDSA cycle two introduced two smart buttons within the endocrine notes. PDSA cycle three focused on standardizing hydrocortisone stress doses.

Results: Initial documentation targets were met for all AI management components except for the crisis dose. The second target was only met for the home stress dose. Implementing the smart buttons aided in reaching the second target for home daily and home stress doses. Dose standardization targets were achieved in all categories except for the on-going crisis dose. A follow up survey after an in-service for non-endocrine providers showed increased knowledge of locating hydrocortisone stress dosing recommendations within the EHR.

Conclusions: With the assistance of technology, this quality improvement project ultimately enhanced communication through the standardization of documentation and individualized hydrocortisone stress dosing for children with AI. Although not all secondary targets were met, there was meaningful improvement in documentation and stress dose standardization compliance.

Keywords: adrenal insufficiency; hydrocortisone; quality improvement; standardization; stress dosing.

MeSH terms

  • Adrenal Insufficiency* / drug therapy
  • Child
  • Electronic Health Records
  • Humans
  • Hydrocortisone* / therapeutic use
  • Patient Compliance
  • Reference Standards

Substances

  • Hydrocortisone