Synthesis of a water-stable fluorescence CsPbBr3 perovskite by dual-supersaturated recrystallization method and tuning the fluorescence spectrum for selective detection of folic acid

Jin-Zhou Liu; Yan-Bo Fu; Ni Yang; Qiu-Lin Wen; Rong Sheng Li; Jian Ling; Qiue Cao

doi:10.1016/j.saa.2023.123586

Synthesis of a water-stable fluorescence CsPbBr₃ perovskite by dual-supersaturated recrystallization method and tuning the fluorescence spectrum for selective detection of folic acid

Spectrochim Acta A Mol Biomol Spectrosc. 2024 Feb 5:306:123586. doi: 10.1016/j.saa.2023.123586. Epub 2023 Oct 29.

Authors

Jin-Zhou Liu¹, Yan-Bo Fu¹, Ni Yang¹, Qiu-Lin Wen¹, Rong Sheng Li¹, Jian Ling², Qiue Cao¹

Affiliations

¹ Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, National Demonstration Center for Experimental Chemistry and Chemical Engineering Education (Yunnan University), School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
² Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, National Demonstration Center for Experimental Chemistry and Chemical Engineering Education (Yunnan University), School of Chemical Science and Technology, Yunnan University, Kunming 650091, China. Electronic address: lingjian@ynu.edu.cn.

PMID: 37922854
DOI: 10.1016/j.saa.2023.123586

Abstract

As an excellent fluorescent material, cesium lead halide perovskite nanocrystals (PNCs) is rarely used for analytical purposes because the PNCs are unstable in polar solvents, especially water. Developing a new synthesis method to prepare water-stable PNCs makes it promising for the detection of analytes in aqueous solutions. Herein, by using the solubility difference of the precursors in different solvents, we successfully synthesized water-stable CsPbBr₃ PNCs by a dual-supersaturated recrystallization method at room temperature. We also found that the fluorescence of the as-prepared CsPbBr₃ PNCs could be quenched by some small organic molecules, such as folic acid (FA) and dopamine (DA). By using a chloride-induced anion exchange reaction method, the fluorescence emission peak of the CsPbBr₃ PNCs could be tuned from 518 to 418 nm and the emission color changed from green to blue. The blue emission chloride-exchanged PNCs have a good selectivity for only FA and a good linear relationship is established between the fluorescence quenching rate of the PNCs and concentration of FA from 10.0 to 140.0 μM, with a limit of detection (LOD) of 0.9 μM. This work expanded the applications of PNCs in the field of analytical chemistry and also proposed a new strategy for improving selectivity by tuning the emission spectrum of a fluorescent probe.

Keywords: Fluorescence; Folic acid; Perovskite nanocrystals; Recrystallization; Selective detection.