Gender differences in the prevalence of stimulant misuse in the United States: 2015-2019

Am J Addict. 2024 May;33(3):283-289. doi: 10.1111/ajad.13501. Epub 2023 Nov 4.

Abstract

Background and objectives: The gender gap in prevalence of substance-use disorders has narrowed. However, gender differences in stimulant misuse have not been well-characterized in recent years. The aim of this study was to quantify gender differences in past-year stimulant misuse and stimulant-use disorder, separated by stimulant type (cocaine/crack, prescription stimulants, and methamphetamine). In an exploratory aim, we investigated whether gender differences were moderated by age or sexual orientation.

Methods: We combined data from the National Survey on Drug Use and Health from 2015 to 2019 (unweighted N = 282,768) to test gender differences in the prevalence of past-year stimulant misuse.

Results: Results indicated that stimulant misuse was significantly more prevalent in men than women for all stimulant types for both past-year use and past-year use disorder. The magnitude of this sex difference was smallest for prescription stimulants, where men had 1.37 times higher odds of past-year misuse and no gender difference was observed in the prevalence of prescription stimulant-use disorder. The magnitude of gender differences also varied based on both age and sexual orientation.

Conclusions and scientific significance: Illicit stimulant misuse continues to be more common in men than in women; however, gender differences are more modest for prescription stimulant misuse, suggesting a narrowing of this historical gender difference.

MeSH terms

  • Central Nervous System Stimulants* / therapeutic use
  • Female
  • Humans
  • Male
  • Methamphetamine*
  • Prescription Drug Misuse*
  • Prevalence
  • Sex Factors
  • Substance-Related Disorders* / drug therapy
  • Substance-Related Disorders* / epidemiology
  • United States / epidemiology

Substances

  • Central Nervous System Stimulants
  • Methamphetamine