In adults with BMI ≥27 kg/m2 and type 2 diabetes, adding tirzepatide to a lifestyle intervention increased weight loss at 72 wk

Ann Intern Med. 2023 Nov;176(11):JC129. doi: 10.7326/J23-0089. Epub 2023 Nov 7.

Abstract

Garvey WT, Frias JP, Jastreboff AM, et al; SURMOUNT-2 investigators. Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. Lancet. 2023;402:613-626. 37385275.

Publication types

  • Comment

MeSH terms

  • Adult
  • Body Mass Index
  • Clinical Trials, Phase III as Topic
  • Diabetes Mellitus, Type 2* / complications
  • Diabetes Mellitus, Type 2* / drug therapy
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Life Style
  • Multicenter Studies as Topic
  • Randomized Controlled Trials as Topic
  • Tirzepatide
  • Weight Loss

Substances

  • Hypoglycemic Agents
  • Tirzepatide