Releasing hidden MAMPs from precursor proteins in plants

Trends Plant Sci. 2024 Apr;29(4):428-436. doi: 10.1016/j.tplants.2023.09.013. Epub 2023 Nov 7.

Abstract

The recognition of pathogens by plants at the cell surface is crucial for activating plant immunity. Plants employ pattern recognition receptors (PRRs) to detect microbe-associated molecular patterns (MAMPs). However, our knowledge of the release of peptide MAMPs from their precursor proteins is very limited. Here, we explore seven protein precursors of well-known MAMP peptides and discuss the likelihood of processing being required for their recognition based on structural models and public knowledge. This analysis indicates the existence of multiple extracellular events that are likely pivotal for pathogen perception but remain to be uncovered.

Publication types

  • Review

MeSH terms

  • Plant Diseases
  • Plant Immunity*
  • Plants* / metabolism
  • Receptors, Pattern Recognition / metabolism

Substances

  • Receptors, Pattern Recognition