Segmental Reflex, Long Latency Reflex, and Mixed Nerve Silent Period in Dystonia

Can J Neurol Sci. 2023 Nov 13:1-5. doi: 10.1017/cjn.2023.313. Online ahead of print.

Abstract

We hypothesized that "long latency reflexes" (LLRs), associated segmental reflex (SR), and mixed nerve silent periods (MnSPs) recorded on the distal upper extremity muscles would behave differently in patients with cervical dystonia and focal hand dystonia. We enrolled patients with cervical dystonia, generalized dystonia, focal hand dystonia, and healthy individuals. We recorded SR, LLRs, and MnSPs. The mean amplitude of SR on the affected side of focal hand dystonia was significantly lower (p = 0.010). The parameters related to LLRs and MnSPs were not different between groups. We suggest, using SR, LLRs, and MnSPs, we could not show an electrophysiological signature specific to dystonia.

Keywords: Dystonia; focal hand dystonia; long latency reflex; mixed nerve silent period; segmental reflex.