Microglia in Central Control of Metabolism

Physiology (Bethesda). 2024 Jan 1;39(1):0. doi: 10.1152/physiol.00021.2023. Epub 2023 Nov 14.


Beyond their role as brain immune cells, microglia act as metabolic sensors in response to changes in nutrient availability, thus playing a role in energy homeostasis. This review highlights the evidence and challenges of studying the role of microglia in metabolism regulation.

Keywords: diet-induced obesity; glial; hypothalamus; metabolism.

Publication types

  • Review

MeSH terms

  • Energy Metabolism / physiology
  • Homeostasis / physiology
  • Humans
  • Hypothalamus / metabolism
  • Microglia* / metabolism
  • Obesity*