A novel hollow CuMn-PBA@NiCo-LDH nanobox for efficient detection of glucose in food

Xin Tang; Xiangwei Yuan; Yao Jin; Jiaying Wu; Chengshuang Ling; Ke Huang; Liping Zhu; Xiaoli Xiong

doi:10.1016/j.foodchem.2023.137969

A novel hollow CuMn-PBA@NiCo-LDH nanobox for efficient detection of glucose in food

Food Chem. 2024 Apr 16:438:137969. doi: 10.1016/j.foodchem.2023.137969. Epub 2023 Nov 10.

Authors

Xin Tang¹, Xiangwei Yuan², Yao Jin², Jiaying Wu², Chengshuang Ling², Ke Huang¹, Liping Zhu³, Xiaoli Xiong⁴

Affiliations

¹ Key Laboratory of Land Resources Evaluation and Monitoring in Southwest, Ministry of Education, Sichuan Normal University, Chengdu 610068, China; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, Sichuan, China.
² College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, Sichuan, China.
³ Key Laboratory of Land Resources Evaluation and Monitoring in Southwest, Ministry of Education, Sichuan Normal University, Chengdu 610068, China; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, Sichuan, China. Electronic address: zhulp@sicnu.edu.cn.
⁴ Key Laboratory of Land Resources Evaluation and Monitoring in Southwest, Ministry of Education, Sichuan Normal University, Chengdu 610068, China; College of Chemistry and Materials Science, Sichuan Normal University, Chengdu 610068, Sichuan, China. Electronic address: xiongxiaoli2000@163.com.

PMID: 37976880
DOI: 10.1016/j.foodchem.2023.137969

Abstract

Designing a rapid and sensitive glucose detection method is of great significance to public health. Herein, hollow CuMn-PBA@NiCo-LDH nanoboxes (CuMn-PBA@NiCo-LDH NBs) were prepared using acid etching, cation exchange, and reflux method. The modified electrode exhibited outstanding electrocatalytic performance for glucose oxidation due to the unique hollow nanostructure and synergistic effects. The CuMn-PBA@NiCo-LDH NBs electrode displayed excellent electrocatalytic oxidation activity for glucose in an alkaline solution. Under optimal conditions, the electrode achieved a wide linear range (0.0005-1 mmol L^-1, and 1-7 mmol L^-1) and high sensitivity (10,300 μA L/mmol cm^-2 and 5310 μA L/mmol cm^-2), with a limit of detection (LOD) of 19 nmol L^-1. The feasibility of the sensor applied to the detection of glucose was verified in real food samples through spiked recovery experiments. This electrode material offers an alternative method for the non-enzymatic glucose sensors.

Keywords: Glucose; Nanobox; Non-enzymatic sensor; Prussian blue analogue.

MeSH terms

Electrochemical Techniques / methods
Glucose* / chemistry
Limit of Detection
Nanostructures* / chemistry
Oxidation-Reduction

Substances

Glucose