Pantailocins: phage-derived bacteriocins from Pantoea ananatis and Pantoea stewartii subsp. indologenes

Appl Environ Microbiol. 2023 Dec 21;89(12):e0092923. doi: 10.1128/aem.00929-23. Epub 2023 Nov 20.

Abstract

Phage-derived bacteriocins (tailocins) are ribosomally synthesized structures produced by bacteria in order to provide advantages against competing strains under natural conditions. Tailocins are highly specific in their target range and have proven to be effective for the prevention and/or treatment of bacterial diseases under clinical and agricultural settings. We describe the discovery and characterization of a new tailocin locus encoded within genomes of Pantoea ananatis and Pantoea stewartii subsp. indologenes, which may enable the development of tailocins as preventative treatments against phytopathogenic infection by these species.

Keywords: Pantoea ananatis; Pantoea stewartii; phage-derived bacteriocin; tailocins.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bacteriocins*
  • Pantoea* / genetics
  • Plant Diseases / microbiology

Substances

  • Bacteriocins

Supplementary concepts

  • Pantoea stewartii subsp. indologenes
  • Pantoea ananatis