Case Report: The Use of In Vivo Confocal Microscopy for Diagnosis and Monitoring in a Rare Case of Ancaliia algerae Microsporidial Keratitis in New South Wales, Australia

Am J Trop Med Hyg. 2023 Nov 20;110(1):87-89. doi: 10.4269/ajtmh.23-0474. Print 2024 Jan 3.


We describe the successful management of Ancaliia Algerae microsporidial keratitis in an immunosuppressed 54-year-old woman with refractory linear IgA disease. The case highlights the challenges in diagnosis and management of this infection in immunocompromised individuals and emphasizes the usefulness of in vivo confocal microscopy as a novel, noninvasive tool to aid in the diagnosis and monitoring of microsporidial keratitis. We also discuss the possible mode of acquisition of this rare infection.

Publication types

  • Case Reports

MeSH terms

  • Australia
  • Eye Infections, Fungal* / diagnosis
  • Eye Infections, Fungal* / drug therapy
  • Female
  • Humans
  • Keratitis* / diagnosis
  • Keratitis* / drug therapy
  • Microscopy, Confocal
  • Middle Aged
  • New South Wales