Malignant pleural effusion due to angiosarcoma: A rare entity

JAAPA. 2023 Dec 1;36(12):1-4. doi: 10.1097/01.JAA.0000977676.98481.5e.


Angiosarcoma is a rare and aggressive vascular malignancy that typically originates in the skin or soft tissue of the body. It is known to have a propensity for metastasis to the lung parenchyma in the form of pulmonary nodules and cavitary lesions; however, a less commonly described entity is in the form of a malignant pleural effusion. Management of a malignant pleural effusion due to angiosarcoma presents a unique challenge. This article describes the challenges faced during one patient's diagnostic and treatment course, and the anticipated future complications of his aggressive disease.

MeSH terms

  • Hemangiosarcoma* / diagnosis
  • Hemangiosarcoma* / secondary
  • Humans
  • Lung / pathology
  • Lung Neoplasms* / complications
  • Lung Neoplasms* / diagnosis
  • Lung Neoplasms* / pathology
  • Pleural Effusion*
  • Pleural Effusion, Malignant* / complications
  • Pleural Effusion, Malignant* / therapy