Brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum mimicking acute stroke

Anaerobe. 2023 Dec:84:102801. doi: 10.1016/j.anaerobe.2023.102801. Epub 2023 Nov 23.

Abstract

We described a case of a 65-year-old man with a brain abscess caused by Porphyromonas gingivalis and Eubacterium nodatum. The patient presented right central facial nerve palsy, mutism and right hemiparesis at the examination. The patient underwent a left frontal craniotomy with evacuation of the brain abscess. Specimens were collected for microbiological analysis and intravenous treatment was started with levetiracetam, dexamethasone, meropenem (1 g/8 h) and linezolid (600 mg/12 h). After identification of anaerobic bacteria the antibiotic treatment was changed to piperacillin/tazobactam (4 g/0,5 g/8 h), fulfilling 8 weeks of antibiotic with good clinical and radiological evolution.

Keywords: Brain abscess; Eubacterium nodatum; Porphyromonas gingivalis; Stroke.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Bacteria, Anaerobic
  • Brain Abscess* / diagnosis
  • Brain Abscess* / drug therapy
  • Brain Abscess* / microbiology
  • Eubacterium
  • Humans
  • Male
  • Porphyromonas gingivalis
  • Stroke* / drug therapy

Substances

  • Anti-Bacterial Agents