We investigate the synergistic effect of Moringa oleifera and Allium sativum on hyperlipidemic patients. It was a randomized controlled trial. The sample size of this study was 60 patients who were divided into four equal groups (n=15) through a random sampling technique. Pre assessment of all participants was conducted at the start of the research. The control group (group A) received atorvastatin 10mg QD as well as placebo capsules. The treatment group 1 (group B) received atorvastatin 10mg QD as well as Moringa oleifera 2g (capsule 1g BID). Treatment group 2 (group C) received atorvastatin 10mg QD as well as Allium sativum 2g (capsule 1g BID). Lastly, treatment group 3 (Group D) received atorvastatin 10mg QD as well as combined Moringa oleifera 2g (capsule 1g BID) and Allium sativum 2g (capsule 1g BID). After an intervention of 45 days, post assessment was conducted. The results showed total cholesterol and triglycerides and low-density lipoprotein of participants of treatment group 3 who received both MO and AS were statistically significant (p<0.05). The group that was on Moringa oleifera supplements alone was found to be statistically significant (p<0.05). This study concluded that Moringa oleifera and Allium sativum considerably improved the BMI and lipid profile of participants.