Comparison of low-level laser therapy and standard treatment for temporomandibular disorders: An assessment of therapeutic and placebo effects

J Oral Rehabil. 2024 Apr;51(4):657-665. doi: 10.1111/joor.13634. Epub 2023 Nov 27.

Abstract

Background: Despite extensive research on the use of low-power lasers for TMD treatment, the extent of their effectiveness remains uncertain.

Objective: This study aimed to investigate the therapeutic or placebo effect of LLLT for TMD, and to compare it with standard treatment methods. A unique aspect of this study was the inclusion of a control group that received only standard treatment, allowing for an assessment of the placebo effect of LLLT.

Methods: A total of 42 patients with TMD were referred to Kerman Dental School Pain Clinic and were randomly assigned to three groups: group A received LLLT, group B was a placebo group and group C was a control group that received only standard treatment. The laser groups received gallium-aluminium-arsenide laser treatment twice a week for 10 sessions. Patients' jaw movement rate indicators and VAS index were evaluated at the start of treatment, and indicators were re-recorded every week for 5 weeks. SPSS 21 was used for statistical analysis, including ANOVA and Tukey's post hoc tests for inter-group comparisons. The repeated measurement test was used to analyse the data.

Results: All groups showed significant improvement in VAS indicators (p = .0001), lateral jaw movements (p = .0001), forward jaw movement (p = .007) but not for maximum mouth opening. No significant difference was observed between the groups at the end of the study (p = .000).

Conclusion: Our study provides insights into LLLT's effectiveness for TMD, suggesting it cannot replace standard treatment alone. These findings contribute to the literature and emphasise the importance of including a control group in future studies to assess the placebo effect of LLLT.

Keywords: LLLT; low level laser therapy; physical therapy modality; placebo response; temporomandibular disorder.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Humans
  • Low-Level Light Therapy*
  • Placebo Effect
  • Temporomandibular Joint Disorders* / radiotherapy