Comparison of Serum Per- and Polyfluoroalkyl Substances Concentrations in Incumbent and Recruit Firefighters and Longitudinal Assessment in Recruits

J Occup Environ Med. 2024 Mar 1;66(3):202-211. doi: 10.1097/JOM.0000000000003020. Epub 2023 Nov 3.

Abstract

Objective: Firefighters are occupationally exposed to per- and polyfluoroalkyl substances (PFAS). This study objective was to compare serum PFAS concentrations in incumbent and recruit firefighters and evaluate temporal trends among recruits.

Methods: Serum PFAS concentrations were measured in 99 incumbent and 55 recruit firefighters at enrollment in 2015-2016, with follow-up 20 to 37 months later for recruits. Linear and logistic regression and linear mixed-effects models were used for analyses. Fireground exposure impact on PFAS concentrations was investigated using adjusted linear and logistic regression models.

Results: Incumbents had lower n-PFOA and PFNA than recruits and most PFAS significantly decreased over time among male recruits. No significant links were found between cumulative fireground exposures and PFAS concentrations.

Conclusions: Serum PFAS concentrations were not increased in incumbent firefighters compared with recruits and were not associated with cumulative fireground exposures.

MeSH terms

  • Alkanesulfonic Acids*
  • Data Collection
  • Environmental Pollutants*
  • Firefighters*
  • Fluorocarbons*
  • Humans
  • Linear Models
  • Male

Substances

  • Environmental Pollutants
  • Fluorocarbons
  • Alkanesulfonic Acids