Research progress on the predictive role of sarcopenia in the course and prognosis of inflammatory bowel disease

Yang Liu; Linglin Tian

doi:10.7717/peerj.16421

Research progress on the predictive role of sarcopenia in the course and prognosis of inflammatory bowel disease

PeerJ. 2023 Nov 22:11:e16421. doi: 10.7717/peerj.16421. eCollection 2023.

Authors

Yang Liu¹, Linglin Tian²

Affiliations

¹ Shanxi Medical University, Taiyuan, Shanxi, China.
² Department of Gastroenterology, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.

Abstract

Sarcopenia is a syndrome characterized by a progressive and extensive decrease in skeletal muscle quality and function. With the development of imaging technology in recent years, the understanding and research on the pathogenesis, diagnosis, and evaluation of sarcopenia have gradually improved. More than one-third of patients with inflammatory bowel disease (IBD) have sarcopenia (Ryan et al., 2019), and as a new and unique body composition evaluation index, it is critical for predicting the clinical course, prognosis and postoperative complications of patients with IBD. However, there are limited research summarizing the prevalence of sarcopenia among IBD. Furthermore, there is a scarcity of studies establishing the precise criteria for diagnosing sarcopenia in these patients. This article summarizes the evaluation of sarcopenia and its recent advancements in predicting the course and prognosis of IBD.

Keywords: Inflammatory bowel disease; Sarcopenia; Skeletal muscle index.

MeSH terms

Body Composition
Humans
Inflammatory Bowel Diseases* / complications
Muscle, Skeletal
Prognosis
Sarcopenia* / diagnosis

Grants and funding

This work was supported by the General Project of Shanxi Natural Science Foundation (202103021224397). Linglin Tain provided financial support for the conduct of the research. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.