Campylobacter jejuni uses energy taxis and a dehydrogenase enzyme for l-fucose chemotaxis

mBio. 2023 Nov 30;14(6):e0273223. doi: 10.1128/mbio.02732-23. Online ahead of print.


In this study, we identify a separate role for the Campylobacter jejuni l-fucose dehydrogenase in l-fucose chemotaxis and demonstrate that this mechanism is not only limited to C. jejuni but is also present in Burkholderia multivorans. We now hypothesize that l-fucose energy taxis may contribute to the reduction of l-fucose-metabolizing strains of C. jejuni from the gastrointestinal tract of breastfed infants, selecting for isolates with increased colonization potential.

Keywords: Campylobacter jejuni; chemotaxis; energy taxis; l-fucose.